结构基因组学研究与核磁共振

各种生物的基因组DNA测序计划的完成，将结构生物学带入了结构基因组学时代.结构基因组学是对所有基因组产物结构的系统性测定，它运用高通量的选择、表达、纯化以及结构测定和计算分析手段，为基因组的每个蛋白质产物提供实验测定的结构或较好的理论模型，这将加速生命科学各个领域的研究.生物信息学、基因工程、结构测定技术等的发展为结构基因组学研究提供了保证.近年来核磁共振在技术方法上的进展，使其成为结构基因组学高通量结构分析中的一个关键方法.

Structural Genomics and Nuclear Magnetic Resonance

The nearly close of sequencing stages of the various genome projects transforms structural biology into structural genomics. Structural genomics is the systematic determination of all genome products' structures. It uses high-throughput selection, expression, purification, structure determination and computational analysis to provide an experimental structure or a good model for every protein in all completed genomes, that will accelerate scientific study in all areas of biological science. The developments of bioinformatics, gene engineering and structure determination techniques provide the guarantee for structural genomics. Recent developments in the technology of nuclear magnetic resonance make it as a key method of high-throughput structural analysis in structural genomics.