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Development and use of solid-phase test-systems for the detection of O-antigen of Shigella sonnei and Shigella flexneri
Authors:I O Triasuchev  A G Davydov  V S Burkin  V I Pokrovski?  T V Pukhova
Abstract:The possibility of the diagnosis of dysentery caused by S. sonnei and S. flexneri, as well as the determination of the dynamics of the distribution of specific O-antigen in the patient's body, by means of the enzyme-linked immunosorbent assay system developed on the basis of antibody preparations obtained by immunosorption has been studied. The study has shown that for better diagnosis the use of fecal extracts is preferable in assays; when used in combination with bacteriological analysis, these assays make it possible to increase the confirmation of the diagnosis of dysentery by several fold.
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