Cytotoxic alpha-pyrones from Xylaria hypoxylon |
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Authors: | Schüffler Anja Sterner Olov Anke Heidrun |
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Institution: | Institute of Biotechnology and Drug Research, Erwin-Schr?dinger-Str. 56, D-67663 Kaiserslautern, Germany. |
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Abstract: | Two new alpha-pyrone derivatives, xylarone (1) and 8,9-dehydroxylarone (2) possessing cytotoxic activities, were isolated from the culture fluid of submerged cultures of the ascomycete Xylaria hypoxylon, strain A27-94. Their structures were elucidated by spectroscopic methods. |
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