枇杷花茶水提物的镇咳、抗炎与抗氧化作用研究

采用小鼠氨水致咳法研究枇杷花茶水提物镇咳效果，以二甲苯致小鼠耳肿胀法研究其抗炎效果，并从枇杷花茶的还原能力及对超氧阴离子和羟自由基的清除作用分析枇杷花茶水提物的抗氧化效果。结果表明，枇杷花茶的水提物高剂量组(3000 mg·kg-1)、低剂量组(700 mg·kg-1)均有镇咳抗炎效果，水提物的浓度越高，效果越好。各浓度枇杷花茶水提物均表现出一定的还原能力，对于羟基自由基和超氧阴离子都有一定的清除效果。其中，20 mg·mL-1水提物还原效果最好(吸光值0.903)，超过0.2 mg·mL-1抗坏血酸(吸光值0.814)；10 mg·mL-1的水提物对超氧阴离子的清除率为47.32%；20 mg·mL-1水提物对于羟基自由基的清除效果非常明显，清除率为91.62%。枇杷花茶水提物镇咳、抗炎、抗氧化效果明显。

Study on Antitussive,Anti-inflammatory and Antioxidant Effects of Aqueous Extracts of Loquat Flower Tea

The antitussive, anti-inflammatory and antioxidant function of loquat flower tea were studied by the methods of cough of mice stimulated by ammonia, xylene-induced ear acute inflammatory and scavenging capability of superoxide anion free radical and hydroxyl free radical, total antioxidant capability. The results showed that both high dose group (3000 mg·kg-1) and low dose group (700 mg·kg-1) of loquat flower tea had antitussive and anti-inflammatory effect, with high doses more effective. All concentrations of water extract showed certain reduction capacities, and had scavenging effects on hydroxyl free radical and superoxide anion. The water extract (20 mg·mL-1) had the best effect (absorbance value 0.903), better than 0.2 mg·mL-1 VC (absorbance value 0.814). The scavenging rate to superoxide anion of the 10 mg·mL -1 water extract was 47.32%, and the scavenging effect on hydroxyl radical of 20 mg·mL-1 water extract was obvious, which was 91.62%. The water extract of loquat tea had strong antitussive and anti-inflammatory, antioxidant effect.