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Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA‐PK |
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| Authors: | Benu Brata Das Smitha Antony Shalu Gupta Thomas S Dexheimer Christophe E Redon Susan Garfield Yosef Shiloh Yves Pommier |
| Institution: | 1. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;2. Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;3. The David and Inez Meyers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel |
| Abstract: | |
| Keywords: | camptothecin DNA repair γ H2AX Topoisomerase 1 XRCC1 |