A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L |
| |
Authors: | Bilan Maria I Grachev Alexey A Ustuzhanina Nadezhda E Shashkov Alexander S Nifantiev Nikolay E Usov Anatolii I |
| |
Affiliation: | N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninskii prosp 47, 119991 Moscow, Russian Federation. |
| |
Abstract: | A fucoidan fraction consisting of L-fucose, sulfate, and acetate in a molar proportion of 1:1.21:0.08 was isolated from the brown seaweed Fucus distichus collected from the Barents Sea. The 13C NMR spectrum of the fraction was typical of regular polysaccharides containing disaccharide repeating units. According to 1D and 2D 1H and 13C NMR spectra, the fucoidan molecules are built up of alternating 3-linked alpha-L-fucopyranose 2,4-disulfate and 4-linked alpha-L-fucopyranose 2-sulfate residues: -->3)-alpha-L-Fucp-(2,4-di-SO3-)-(1-->4)-alpha-L-Fucp-(2SO3-)-(1-->. The regular structure may be only slightly masked by random acetylation and undersulfation of several disaccharide repeating units. |
| |
Keywords: | Fucoidan NMR Disaccharide repeating unit Seaweed Brown algae Fucus distichus |
本文献已被 ScienceDirect PubMed 等数据库收录! |