Structure and evolution of the plant cation diffusion facilitator family of ion transporters |
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| Authors: | Jeffery L Gustin Michael J Zanis David E Salt |
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| Affiliation: | (1) Department of Horticulture and Landscape Architecture, Purdue University, 625 Agricultural Mall Drive, West Lafayette, IN 47907-2010, USA;(2) Department of Botany and Plant Pathology, Purdue University, 915 West State Street, West Lafayette, IN 47907-2054, USA;(3) Horticultural Sciences Department, University of Florida, 1117 Fifield Hall, Gainesville, FL 32611-0690, USA |
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| Abstract: | Background Members of the cation diffusion facilitator (CDF) family are integral membrane divalent cation transporters that transport metal ions out of the cytoplasm either into the extracellular space or into internal compartments such as the vacuole. The spectrum of cations known to be transported by proteins of the CDF family include Zn, Fe, Co, Cd, and Mn. Members of this family have been identified in prokaryotes, eukaryotes, and archaea, and in sequenced plant genomes. CDF families range in size from nine members in Selaginella moellendorffii to 19 members in Populus trichocarpa. Phylogenetic analysis suggests that the CDF family has expanded within plants, but a definitive plant CDF family phylogeny has not been constructed. |
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