| Sorting and Processing of the Alzheimer’s Disease Amyloid Precursor Protein Mediated by the AP-4 Complex |
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| 作者姓名： | Patricia V.Burgos Gonzalo A.Mardones Luis L.P.daSilva Yogikala Prabhu Juan S.Bonifacino |
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| 作者单位： | Cell Biology and Metabolism Program;Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health;Bethesda;MD 20892;USA; |
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| 摘 要： | Proteolytic processing of the transmembrane amyloid precursor protein (APP) to aggregation-prone amyloid-β (Aβ) peptide underlies the development of Alzheimer’s disease.
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