Proteomic profiling of <Emphasis Type="Italic">Pseudomonas aeruginosa</Emphasis> AES-1R,PAO1 and PA14 reveals potential virulence determinants associated with a transmissible cystic fibrosis-associated strain期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Proteomic profiling of <Emphasis Type="Italic">Pseudomonas aeruginosa</Emphasis> AES-1R,PAO1 and PA14 reveals potential virulence determinants associated with a transmissible cystic fibrosis-associated strain

Authors:	Nathan J Hare Nestor Solis Christopher Harmer N Bishara Marzook Barbara Rose Colin Harbour Ben Crossett Jim Manos Stuart J Cordwell

Institution:	(1) School of Molecular Bioscience, The University of Sydney, Sydney, 2006, Australia;(2) Discipline of Immunology and Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia;(3) Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia;(4) School of Molecular Bioscience, Building GO8, Maze Crescent, The University of Sydney, Sydney, 2006, Australia

Abstract:	Background Pseudomonas aeruginosa is an opportunistic pathogen that is the major cause of morbidity and mortality in patients with cystic fibrosis (CF). While most CF patients are thought to acquire P. aeruginosa from the environment, person-person transmissible strains have been identified in CF clinics worldwide. The molecular basis for transmissibility and colonization of the CF lung remains poorly understood.

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