| 腹主动脉瘤生长过程的蠕变力学模型 |
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| 引用本文： | 蒋之森,袁丁,庞霖. 腹主动脉瘤生长过程的蠕变力学模型[J]. 生物化学与生物物理进展, 2016, 43(5): 523-531 |
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| 作者姓名： | 蒋之森 袁丁 庞霖 |
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| 作者单位： | 四川大学物理科学与技术学院，成都 610064,四川大学华西医院，成都 610041,四川大学物理科学与技术学院，成都 610064 |
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| 基金项目： | 国家自然科学基金资助项目(61377054) |
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| 摘 要： | 基于增强对腹主动脉瘤生长过程的理解、为腹主动脉瘤临床手术提供参考的目的,本文根据腹主动脉瘤的生长物理机制,提出了以蠕变力学为基础模拟腹主动脉瘤生长过程的模型.建立了腹主动脉瘤简化模型,利用有限元方法进行模拟计算.结果显示蠕变模型能够有效模拟腹主动脉瘤生长过程中的形态变化.参数优化模型模拟结果符合临床统计数据所示的腹主动脉瘤生长过程.本文还讨论了腹主动脉材料力学参数对模型的影响.
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| 关 键 词： | 腹主动脉瘤，蠕变，生长速率 |
| 收稿时间： | 2015-10-21 |
| 修稿时间： | 2016-02-26 |
Creep Model of The Growth of Abdominal Aortic Aneurysm |
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| JIANG Zhi-Sen,YUAN Ding and PANG Lin. Creep Model of The Growth of Abdominal Aortic Aneurysm[J]. Progress In Biochemistry and Biophysics, 2016, 43(5): 523-531 |
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| Authors: | JIANG Zhi-Sen YUAN Ding PANG Lin |
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| Affiliation: | College of Physical Science and Technology, Sichuan University, Chengdu 610064, China,West China Hospital, Sichuan University, Chengdu 610041, China and College of Physical Science and Technology, Sichuan University, Chengdu 610064, China |
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| Abstract: | In order to further understand the growth of abdominal aortic aneurysm (AAA) and to provide a reference for clinical AAA surgery, we put forward a model based on the characteristic of the growth of AAA and creep mechanics. We establish a simplified model of AAA and use finite element analysis to simulate its growth. Our results show that the proposed model can simulate the morphological change of AAA during its growth and the optimized model has a good result of AAA growth process which compliance with clinical data. We also discussed the influence of parameters of the abdominal aorta on the model itself and suggest the future research direction. |
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| Keywords: | abdominal aortic aneurysm creep growing rate |
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