Distinctions in DNA and protein profiles among clinical isolates of Mycoplasma pneumoniae. |
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| Authors: | C J Su S F Dallo H Alderman J B Baseman |
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| Affiliation: | Department of Microbiology, University of Texas Health Science Center, San Antonio 78284-7758. |
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| Abstract: | Clinical isolates of Mycoplasma pneumoniae previously shown to exhibit significant sequence divergency in a major 170 kDa adhesin, designated P1, were further characterized using restriction enzyme fingerprinting of genomic DNA and two-dimensional gel electrophoresis of total proteins. Numerous differences in DNA restriction patterns and protein profiles were found, possibly reflecting various degrees of virulence and antigenic potential. |
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