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Heterozygous OT-I mice reveal that antigen-specific CD8+ T cells shift from apoptotic to necrotic killers in the elderly |
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| Authors: | Dorina Zöphel Lea Kaschek Romy Steiner Sandra Janku Hsin-Fang Chang Annette Lis |
| Institution: | 1. Department of Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, 66421 Homburg, Germany;2. Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany |
| Abstract: | |
| Keywords: | adaptive immunity aging apoptosis CD8+ T cells cytotoxicity necrosis OT-I perforin |