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Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing
Authors:Debanjana Maji  Eliezra Glasser  Steven Henderson  Justin Galardi  Mary J Pulvino  Jermaine L Jenkins  Clara L Kielkopf
Institution:Center for RNA Biology, Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Abstract:
Keywords:U2AF2  U2AF65  RNA–  protein interaction  RNA splicing  RNA-binding protein  crystal structure  structure–  function  X-ray crystallography  structural biology  cancer biology  protein structure
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