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Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation |
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| Authors: | Jie Li Jing Zhang Qi Xue Boyang Liu Ran Qin Yiping Li Yue Qiu Rong Wang David Goltzman Dengshun Miao Renlei Yang |
| Institution: | 1. Department of Plastic Surgery, Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China;2. Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China;3. Calcium Research Laboratory, McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec, Canada |
| Abstract: | |
| Keywords: | aging Fbn1 Keap1-Nrf2 signaling osteoporosis pyrroloquinoline quinone |