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Changes in Monoamine Oxidase Activity in Rat Brain During Alloxan Diabetes
Authors:C. S. K. Mayanil  S. M. I. Kazmi  N. Z. Baquer
Affiliation:Hormone and Drug Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
Abstract:Abstract: The effect of alloxan diabetes on the activity of monoamine oxidase was studied in three regions of the rat brain at various time intervals after the onset of diabetes. It was observed that monoamine oxidase activity was decreased at early time intervals after diabetes, followed by a recovery in all three regions of the brain. A reversal of the effect was observed with insulin administration to the diabetic rats.
Keywords:Monoamine oxidase    Brain    Diabetes    Catecholamines    Insulin
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