FLU,an amino acid substitution model for influenza proteins |
| |
| Authors: | Cuong Cao Dang Quang Si Le Olivier Gascuel Vinh Sy Le |
| |
| Institution: | (1) College of Technology, Vietnam National University Hanoi, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam;(2) Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA Hinxton, Cambridge, UK;(3) Methodes et Algorithmes pour la Bioinformatique, LIRMM, CNRS, Universite Montpellier II, Montpellier, France |
| |
| Abstract: | Background The amino acid substitution model is the core component of many protein analysis systems such as sequence similarity search,
sequence alignment, and phylogenetic inference. Although several general amino acid substitution models have been estimated
from large and diverse protein databases, they remain inappropriate for analyzing specific species, e.g., viruses. Emerging
epidemics of influenza viruses raise the need for comprehensive studies of these dangerous viruses. We propose an influenza-specific
amino acid substitution model to enhance the understanding of the evolution of influenza viruses. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
