Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid |
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| Authors: | Devillard Estelle McIntosh Freda M Duncan Sylvia H Wallace R John |
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| Institution: | Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB, United Kingdom. |
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| Abstract: | A survey of 30 representative strains of human gram-positive intestinal bacteria indicated that Roseburia species were among the most active in metabolizing linoleic acid (cis-9,cis-12-18:2). Different Roseburia spp. formed either vaccenic acid (trans-11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis-9,trans-11-18:2 in human tissues and the intestine, respectively. |
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