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Directed optimization of a newly identified squalene synthase from Mortierella alpine based on sequence truncation and site-directed mutagenesis
Authors:Di Huang  Yongpeng Yao  Hang Zhang  Zhu Mei  Ru Wang  Lu Feng  Bin Liu
Affiliation:1. TEDA Institute of Biological Sciences and Biotechnology, Nankai University, TEDA, Tianjin, 300457, People’s Republic of China
2. Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, Tianjin, 300071, People’s Republic of China
3. Tianjin Key Laboratory of Microbial Functional Genomics, Tianjin, 300457, People’s Republic of China
4. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, People’s Republic of China
5. SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072, People’s Republic of China
Abstract:
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