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Acetic acid production by Acetogenium kivui in continuous culture — kinetic studies and computer simulations
Authors:J von Eysmondt  Dj Vasic-Racki  Ch Wandrey
Institution:(1) Institute of Biotechnology, Research Center, W-5170 Jülich, Federal Republic of Germany;(2) Faculty of Technology, University of Zagreb, Zagreb, Yugoslavia;(3) Present address: Hoechst AG, Verfahrenstechnik G 811, Postfach 80 03 20, D-6230 Frankfurt a. M. 80, FRG
Abstract:Summary This work considers the continuous production of acetic acid by the homoacetogenic and thermophilic bacterium Acetogenium kivui. A mathematical model for the growth kinetics has been developed. The unstructured model for growth and product formation includes product and substrate inhibition as well as maintenance energy effects. The associated model parameters have been identified by non-linear optimization and evidenced experimentally in continuous culture as steady-state data. By using a mineral medium with glucose as the energy and carbon source for the bacteria proper carbon balances are available. The model permits good predictions of steady-state concentrations. Offprint requests to: J. von Eysmondt
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