UDP-Galactose:Ceramide Galactosyl Transferase of Isolated Oligodendroglia |
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| Authors: | Angela Carruthers Eric M Carey |
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| Institution: | Department of Biochemistry, The University, Sheffield, U.K. |
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| Abstract: | Abstract: The activity of UDP-galactose:ceramide galactosyl transferase (CGalT) has been studied in isolated oligodendroglia from bovine brain white matter and myelinating rat brain. The specific activity and activity per mg DNA are 4- and 10-fold higher in rat oligodendroglia compared with neuronal perikarya from rat brain, and is higher in oligodendroglia from myelinating rat brain compared with bovine oligodendroglia. In membranes isolated from oligodendroglia, the specific activity decreased in the order endoplasmic reticulum > plasma membrane > myelin. |
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| Keywords: | UDP-galactose: ceramide galactosyl transferase Oligodendroglia Activity Localization |
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