N-azidomethylbenzoyl blocking group in the phosphotriester synthesis of oligoribonucleotides |
| |
Authors: | V. A. Efimov A. V. Aralov S. A. Grachev O. G. Chakhmakhcheva |
| |
Affiliation: | 1.Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,Moscow,Russia |
| |
Abstract: | An effective modification of the phosphotriester method has been developed for the automatic synthesis of DNA and RNA fragments using O-nucleophilic intramolecular catalysis and the 2-(azidomethyl)benzoyl group for the protection of the amino groups of nucleotide heterocyclic bases. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |