<Emphasis Type="Italic">N</Emphasis>-azidomethylbenzoyl blocking group in the phosphotriester synthesis of oligoribonucleotides |
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Authors: | V A Efimov A V Aralov S A Grachev O G Chakhmakhcheva |
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Institution: | 1.Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,Moscow,Russia |
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Abstract: | An effective modification of the phosphotriester method has been developed for the automatic synthesis of DNA and RNA fragments
using O-nucleophilic intramolecular catalysis and the 2-(azidomethyl)benzoyl group for the protection of the amino groups of nucleotide
heterocyclic bases. |
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Keywords: | |
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