The innate immune repertoire in Cnidaria - ancestral complexity and stochastic gene loss |
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| Authors: | David J Miller Georg Hemmrich Eldon E Ball David C Hayward Konstantin Khalturin Noriko Funayama Kiyokazu Agata Thomas CG Bosch |
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| Institution: | (1) ARC Centre of Excellence in Coral Reef Studies and Comparative Genomics Centre, James Cook University, Townsville, Queensland, 4811, Australia;(2) Zoological Institute, Christian-Albrechts-University Kiel, Olshausenstrasse, 24098, Kiel, Germany;(3) ARC Centre for the Molecular Genetics of Development, Research School of Biological Sciences, Australian National University, Canberra, ACT, 2601, Australia;(4) Department of Biophysics, Kyoto University, Kitashirakawa-Oiwake, Sakyo-ku Kyoto, 606-8502, Japan |
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| Abstract: | Background Characterization of the innate immune repertoire of extant cnidarians is of both fundamental and applied interest - it not
only provides insights into the basic immunological 'tool kit' of the common ancestor of all animals, but is also likely to
be important in understanding the global decline of coral reefs that is presently occurring. Recently, whole genome sequences
became available for two cnidarians, Hydra magnipapillata and Nematostella vectensis, and large expressed sequence tag (EST) datasets are available for these and for the coral Acropora millepora. |
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