Androgen receptor CAG repeat polymorphism in males of six non-human primate species |
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Authors: | Mubiru James N Cavazos Nicole Hemmat Peggah Garcia-Forey Magdalena Shade Robert E Rogers Jeffrey |
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Affiliation: | Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. jmubiru@TxBiomed.org |
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Abstract: | Background Androgen receptor [CAG]n microsatellite has been linked to human diseases. Methods Six non‐human primates were genotyped for the [CAG]n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non‐human primates that are polymorphic for the microsatellite are candidate animal models for CAG‐related diseases. |
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Keywords: | baboon chimpanzee macaques mangabey marmoset microsatellite |
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