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Androgen receptor CAG repeat polymorphism in males of six non-human primate species
Authors:Mubiru James N  Cavazos Nicole  Hemmat Peggah  Garcia-Forey Magdalena  Shade Robert E  Rogers Jeffrey
Affiliation:Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. jmubiru@TxBiomed.org
Abstract:Background Androgen receptor [CAG]n microsatellite has been linked to human diseases. Methods Six non‐human primates were genotyped for the [CAG]n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non‐human primates that are polymorphic for the microsatellite are candidate animal models for CAG‐related diseases.
Keywords:baboon  chimpanzee  macaques  mangabey  marmoset  microsatellite
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