The Archaeal P-Type ATPases |
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Authors: | Benoît De Hertogh Anne-Catherine Lantin Philippe V Baret André Goffeau |
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Institution: | Unité de Génétique (GENA), Université Catholique de Louvain, Louvain-la-Neuve, Belgique. |
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Abstract: | A phylogenetic analysis was carried out of a total of 58 P-type ATPases encoded within the genomes of 20 archaea species. Members from six subfamilies were identified including: putative metal-, proton-, calcium-, sodium/potassium-, potassium-, and magnesium/nickel-transporting ATPases. Six novel putative proton-ATPases from archaea species growing under different temperature and pH conditions were shown to have shorter N- and C-termini than those of orthologous yeast or plant proton-ATPases. Moreover recent biochemical data are reviewed that report functional expression of putative archaea metal- or proton-ATPases in bacteria or yeast. |
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Keywords: | Archaea ATPases comparative genomics functional expression phylogeny transport classification |
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