Density distribution of human lymphocytes. I. Results of research on normal lymphoid tissue

The aim of this study was to analyze the density distribution patterns of subsets of normal human lymphocytes. Density distribution was assessed by equilibrium centrifugation on linear polysucrose-metrizoat gradients. Results of the analyses of various subsets of lymphoid cells differing in their degree of cellular maturation and functional activation suggested that their distribution patterns are determined by three independent factors: the derivation, the stage of differenciation and the functional activity.