Suppression of macromolecular biosynthesis in Mycobacterium tuberculosis H37RV by antimannophosphoinositides |
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| Authors: | P.K. Mehta G.K. Khuller |
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| Affiliation: | Freie Universität Berlin, Institut für Biochemie, F.R.G.;Max-Planck-Institut für molekulare Genetik, Ihnestrasse 73, Berlin, F.R.G. |
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| Abstract: | Abstract We examined the extremely thermophilic Gram-negative eubacterium Thermus aquaticus for the presence of plasmid DNA, and detected 5 species. The sizes were determined by electron microscopy and gel electrophoresis. The plasmids, pTA 1-pTA 5, were of respective length: 13.5, 12.4, 11.2, 9.6 and 8.3 kb. Clones were isolated which differed in plasmid distribution. No correlation could be observed between the phenotype or growth behaviour and the presence of plasmids. The function of the plasmid structures still needs to be elucidated. |
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| Keywords: | Thermus aquaticus Restriction Plasmid (Electron microscopy) |
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