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Mytilus edulis Histone Gene Clusters Containing Only H1 Genes
Authors:Birgit Drabent  Jae-Sun Kim  Werner Albig  Eva Prats  Luis Cornudella  Detlef Doenecke
Institution:Institute of Biochemistry and Molecular Cell Biology, Department of Molecular Biology, Georg-August-University G?ttingen, Humboldtallee 23, D-37073 G?ttingen, Germany, DE
Department of Molecular and Cell Biology, Centro de Investigación y Desarrollo del CSIC, Jordi Girona 18-26, E-08034 Barcelona, Spain, ES
Abstract:We isolated five different phage clones containing histone gene clusters with up to five H1 genes per phage clone from a Mytilus edulis genomic library. Among these H1 genes, nine gene types coding for five different H1 proteins have been identified. All H1 histone genes were located on repetitive restriction fragments with only slightly different sizes. The H1 coding regions show highly related sequences, suggesting that the multitude of H1 genes has evolved by gene duplication events. Core histone genes could not be found on these five Mytilus edulis genome fragments. Received: 28 July 1998 / Accepted: 17 May 1999
Keywords::Mytilus edulis—  H1 histone genes —  Gene organization —  Nucleotide sequence
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