| 分别兴奋大鼠内侧和外侧缰核引起痛阈的不同改变 |
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| 引用本文： | 赵华 王绍. 分别兴奋大鼠内侧和外侧缰核引起痛阈的不同改变[J]. 生理学报, 1995, 47(3): 292-296 |
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| 作者姓名： | 赵华 王绍 |
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| 作者单位： | 白求恩医科大学生理教研室 |
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| 摘 要： | （Ｈｂ）与痛觉调制有关，但不同实验室的结果并不一致，本实验目的在于澄清其中原因，实验在戊巴比妥钠浅麻和清醒的大鼠上进行，应用玻璃微电极微量注射Ｌ－谷氨酸（Ｌ－Ｇｌｕ）到内侧缰核（ＭＨｂ）和外侧缰核（ＬＨｂ），利用多种动物模型观察大鼠的痛阈改变，实验结果发现，兴奋ＭＨｂ时痛阈增高，而ＬＨｂ兴奋时痛阈降低。
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| 关 键 词： | 缰核 痛阈 边缘系统 |
DIFFERENT EFFECT OF L-GLUTAMATE MICROINJECTION INTO MEDIAL OR LATERAL HABENULAR NUCLXU ON PAIN THRESHOLD |
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| ZHAO HUA AND WANG SHAO. DIFFERENT EFFECT OF L-GLUTAMATE MICROINJECTION INTO MEDIAL OR LATERAL HABENULAR NUCLXU ON PAIN THRESHOLD[J]. Acta Physiologica Sinica, 1995, 47(3): 292-296 |
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| Authors: | ZHAO HUA AND WANG SHAO |
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| Abstract: | The habenulae (Hb) are related to modulation of pain sensation, but the results from different laboratories are inconsistant. The aim of the present investigation is to clarify the discrepancy. L-Glutamic acid (L-Glu) was microinjected into medial (MHb) and lateral habenular nucleus (LHb) on light anesthetized or conscious rats,and pain threshold was then determined on the different models of animal. The results showed that the activation of MHb increased TFL, whereas activation of LHb decreased TFL. |
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| Keywords: | habenulae tail-flick latency limbic system L-Glutamic acid |
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