Molecular cloning of novel alternatively spliced variants of BCL2L12, a new member of the BCL2 gene family,and their expression analysis in cancer cells |
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| Authors: | Christos K. Kontos Andreas Scorilas |
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| Affiliation: | Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Athens, Greece |
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| Abstract: | |
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| Keywords: | BCL2L12, BCL2-like 12 BH2 domain, BCL2-homology-2 domain BH3-like motif, BCL2-homology-3-like motif HSPB5, heat shock protein beta-5 UV, ultraviolet aa, amino acid(s) HSP70, heat shock 70-kDa protein DFS, disease-free survival OS, overall survival NPC, nasopharyngeal carcinoma CLL, chronic lymphocytic leukemia EST(s), expressed sequence tag(s) cDNA, DNA complementary to RNA CO2, carbon dioxide FBS, fetal bovine serum ku, kilo-units HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid DMEM, Dulbecco's modified Eagle's medium oligo(dT), oligodeoxythymidine DTT, dithiothreitol dNTP, deoxyribonucleoside triphosphate u, unit(s) RNase, ribonuclease PCR, polymerase chain reaction UTR, untranslated region bp, base pair(s) GAPDH, glyceraldehyde-3-phosphate dehydrogenase EtdBr, ethidium bromide ORF, open reading frame PXXP motif, Pro-any-any-Pro motif nt, nucleotide(s) 3D, three-dimensional PTC, premature translation termination codon NMD, nonsense-mediated mRNA decay BH1 domain, BCL2-homology-1 domain BH4 domain, BCL2-homology-4 domain CDKN1A, cyclin-dependent kinase inhibitor 1A ARE, AU-rich element |
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