| Ironic fate: can a banned drug control metal heavies in neurodegenerative diseases? |
| |
| 引用本文： | Cole GM. Ironic fate: can a banned drug control metal heavies in neurodegenerative diseases?[J]. Neuron, 2003, 37(6): 889-890. DOI: 10.1016/S0896-6273(03)00160-0 |
| |
| 作者姓名： | Cole GM |
| |
| 摘 要： |
|
Ironic Fate: Can a Banned Drug Control Metal Heavies in Neurodegenerative Diseases? |
| |
| Cole Greg M. Ironic Fate: Can a Banned Drug Control Metal Heavies in Neurodegenerative Diseases?[J]. Neuron, 2003, 37(6): 889-890. DOI: 10.1016/S0896-6273(03)00160-0 |
| |
| Authors: | Cole Greg M |
| |
| Affiliation: | Greater Los Angeles VA Medical Center, UCLA Alzheimer's Disease Research Center, Sepulveda, CA 91343, USA. |
| |
| Abstract: | In this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene or the metal chelator clioquinol prevent oxidative damage and MPTP toxicity in mice. This raises the issue of specific iron chelators or clioquinol for control of oxidative damage in Parkinson's, Alzheimer's, and other neurodegenerative diseases, but not without safety concerns. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
