Synthesis and free radical scavenging activity of some new spiropyranocoumarins |
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| Authors: | Panteleon Vassiliki Kostakis Ioannis K Marakos Panagiotis Pouli Nicole Andreadou Ioanna |
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| Institution: | Department of Pharmacy, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. |
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| Abstract: | A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1,1-diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine-xanthine oxidase system. |
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