| 幽门螺杆菌感染的分子机制 |
| |
| 引用本文： | 顾青,朱睦元. 幽门螺杆菌感染的分子机制[J]. 细胞生物学杂志, 2006, 28(4): 547-550 |
| |
| 作者姓名： | 顾青 朱睦元 |
| |
| 作者单位： | 浙江工商大学生物工程系，浙江大学生命科学学院 杭州310035 浙江大学生命科学学院，杭州310012，杭州310012 |
| |
| 基金项目： | 国家自然科学基金资助项目(No.30300017)~~ |
| |
| 摘 要： | 幽门螺杆菌(Helicobacterpylori)是居留于人胃上皮组织并引起胃炎、消化性胃溃疡和胃癌的病原菌。近年来,随着幽门螺杆菌全基因组序列的报道和功能基因的研究深入,对幽门螺杆菌的感染的分子、免疫等机制逐渐阐明。现对幽门螺杆菌基因组特点和幽门螺杆菌黏附、毒性因子等对人体感染的分子机制等方面的研究进展做一综述。
|
| 关 键 词： | 幽门螺杆菌 基因组 感染 分子机制 |
| 收稿时间： | 2005-11-18 |
| 修稿时间： | 2006-04-18 |
Molecular Mechanism of Helicobacter pylori Infection |
| |
| Qing Gu,Mu-Yuan Zhu. Molecular Mechanism of Helicobacter pylori Infection[J]. Chinese Journal of Cell Biology, 2006, 28(4): 547-550 |
| |
| Authors: | Qing Gu Mu-Yuan Zhu |
| |
| Affiliation: | 1 Department of Biotechnology, Zhejiang Gong shang University, Hangzhou 310035, China; 2College of Life Sciences, Zhefiang University, Hangzhou 310012, China |
| |
| Abstract: | Helicobacter pylori colonizes the human gastric epithelium and is responsible for gastritis, peptic ulcer, and gastric cancer. In recent years, with publish of the complete genome sequence of H. pylori and deep research of functional genes of this organism, the molecular mechanism of H. pylori infection and the immune response are more in depth understanding. In the paper, We summarize the characteristic of H. pylori genome and molecular mechanism which H. pylori infect human by adhere to the gastric cells and a unique set of virulence factors. |
| |
| Keywords: | Helicobacter pylori genome infection molecular mechanism |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
