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脑膜炎败血伊丽莎白菌及其感染的研究进展
引用本文:陆怡凯,袁舒颖,杨源博,巫祺乐,方子璇,刘岩,陈力,孙桂芹. 脑膜炎败血伊丽莎白菌及其感染的研究进展[J]. 微生物与感染, 2021, 16(2): 110-116. DOI: 10.3969/j.issn.1673-6184.2021.02.006
作者姓名:陆怡凯  袁舒颖  杨源博  巫祺乐  方子璇  刘岩  陈力  孙桂芹
作者单位:浙江中医药大学医学技术与信息工程学院,浙江 杭州310053;复旦大学基础医学院病原生物学系,教育部/卫健委/医科院医学分子病毒学重点实验室,上海 200032
基金项目:国家自然科学基金(31600644)
摘    要:脑膜炎败血伊丽莎白菌(Elizabethkingia meningoseptica,EM)是一种非发酵革兰氏阴性杆菌,为医院感染的重要病原菌之一,近年来其检出率呈上升趋势.EM易感人群主要为有基础疾病、免疫功能低下或缺陷、长期使用抗生素及有侵入性操作等的患者,可引起脑膜炎、菌血症、肺部感染、眼部感染等,其多重耐药性给临...

关 键 词:脑膜炎伊丽莎白菌  生物学特性  感染  临床表现  检测  危险因素

Research progress on Elizabethkingia meningoseptica and infection
LU Yikai,YUAN Shuying,YANG Yuanbo,WU Qile,FANG Zixuan,LIU Yan,CHEN Li,SUN Guiqin. Research progress on Elizabethkingia meningoseptica and infection[J]. Journal of Microbes and Infection, 2021, 16(2): 110-116. DOI: 10.3969/j.issn.1673-6184.2021.02.006
Authors:LU Yikai  YUAN Shuying  YANG Yuanbo  WU Qile  FANG Zixuan  LIU Yan  CHEN Li  SUN Guiqin
Affiliation:1. School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China; 2. Department of Medical Microbiology and Parasitology, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
Abstract:Elizabethkingia meningoseptica (EM), a non-fermented Gram-negative bacterium, is one of the most important pathogens of nosocomial infection. The detection rate has been on the rise in recent years. The susceptible people mainly include the patients with basic diseases, immunodeficiency or deficiency, long-term use of antibiotics, invasive procedures, and so on. EM could cause meningitis, bacteremia, lung infections, eye infections, etc. Its multi-drug resistance has burdened the clinical treatment. Animals could also be infected by EM, like frogs, fish, turtles, pigs, dogs and others. The biological characteristics, infection types, detection methods and risk factors are analyzed in the present paper, which would offer a new insight of EM. Hospitals should focus on the detection, drug resistance and pathogenesis of EM, which would provide the reference for prevention and control of nosocomial infection.
Keywords:Elizabethkingia meningoseptica  Biological characteristics  Infection  Clinical characterization  Detection  Risk factor  
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