| 严重急性呼吸综合征、中东呼吸综合征和2019冠状病毒病治疗研究进展 |
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| 引用本文： | 傅掌璠,艾静文. 严重急性呼吸综合征、中东呼吸综合征和2019冠状病毒病治疗研究进展[J]. 微生物与感染, 2021, 16(3): 214-220. DOI: 10.3969/j.issn.1673-6184.2021.03.009 |
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| 作者姓名： | 傅掌璠 艾静文 |
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| 作者单位： | 复旦大学附属华山医院感染科，上海市传染病与生物安全应急响应重点实验室，国家传染病医学中心，上海 200040 |
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| 基金项目： | 上海市青年科技英才扬帆计划(20YF1404300) |
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| 摘 要： | 严重急性呼吸综合征2019(sever acute respiratory syndrome,SARS)、中东呼吸综合征(Middle East respiratory syndrome,MERS)和2019冠状病毒病(corona virus disease 2019,COVID-19)对全世界人民造成了严重的经济损...
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| 关 键 词： | 严重急性呼吸综合征 中东呼吸综合征 2019冠状病毒病 治疗 |
Research progress of severe acute respiratory syndrome,Middle East respiratory syndrome and corona virus disease 2019 treatment |
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| FU Zhangfan,AI Jingwen. Research progress of severe acute respiratory syndrome,Middle East respiratory syndrome and corona virus disease 2019 treatment[J]. Journal of Microbes and Infection, 2021, 16(3): 214-220. DOI: 10.3969/j.issn.1673-6184.2021.03.009 |
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| Authors: | FU Zhangfan AI Jingwen |
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| Affiliation: | Department of Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, National Medical Center for Infectious Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China |
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| Abstract: | Severe acute respiratory syndrome (sever acute respiratory syndrome, SARS), Middle East respiratory syndrome (middle east respiratory syndrome, MERS), and new coronavirus pneumonia (corona virus disease 2019, COVID-19) have brought serious illnesses to people all over the world. Economic loss and mental injury, given that there are no new cases of SARS and little progress in research, this article focuses on the treatment of MERS and COVID-19. The treatments of MERS and COVID-19 are similar. Nucleoside analogs, lopinavir/ritonavir, neutralizing antibodies, glucocorticoids, and other potential therapies (new use of old drugs) have been used clinically. Due to the wide spread of COVID-19 and the large number of infected people, some new drugs have emerged, such as Remdesivir, REGN-COV2 antibody, LY-CoV555 antibody, etc., but the current effect is not good, and the clinical diagnosis and treatment plan has yet to be improved. This article reviews the research progress in the treatment of SARS, MERS and COVID-19, and provides a theoretical basis for further research on their treatment options, improving treatment effects, and reducing mortality. |
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| Keywords: | Severe acute respiratory syndrome Middle East respiratory syndrome Corona virus disease 2019 Treatment |
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