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在猪12号染色体上定位数量性状位点
引用本文:岳根华,G Moser,H Geldermann.在猪12号染色体上定位数量性状位点[J].遗传学报,2000,27(10):858-865.
作者姓名:岳根华  G Moser  H Geldermann
作者单位:新加坡农业分子生物学院,Department of Animal Breeding and Biotechnology Institute of Animal Husbandary and Animal Breeding,Uinversity of Hohenheim!Germany,Department of Animal Breeding and Biotechnology Institute of Animal Husbandary and Animal Breeding,U
基金项目:欧洲共同体猪基因组项目!(PiGMaP),德国国家科学基金会!(DFG)
摘    要:为了找出猪12号染色体上的数量性状位点,在2个家系中测定了10个遗传标记,并记录了51个重要经济性状。该2家系,一个由欧洲野猪与皮特兰杂交而成,另一个由梅山与皮特兰杂交建成。应用最小二乘法进行了数量性状位点定位,同时进行了生长激素基因型与性状间的相关分析。应用最小二乘法并未发现数量性状位点,而应用相关分析发现生长激素基因型与某些膘情性状高度相关。带有基因型C1A2/C4A2的猪比带有基因型C2A2

关 键 词:数量性状位点  生长激素基因  12号染色体  

Identification of QTL Affecting Important Traits on Porcine Chromosome 12
YUE Gen-Hua,H Bartenschlager,G Moser,H Geldermann.Identification of QTL Affecting Important Traits on Porcine Chromosome 12[J].Journal of Genetics and Genomics,2000,27(10):858-865.
Authors:YUE Gen-Hua  H Bartenschlager  G Moser  H Geldermann
Abstract:To screen the whole porcine chromosome 12 for QTL affecting economically important traits, ten genetic markers were genotyped in two F2 populations generated from the cross of genetically diverse breeds: European Wild pig and commercial pig breed Pietrain (W×P), and Chinese Meishan and Pietrain (M×P). Fifty杘ne traits were recorded. A least squares method was used for chromosome-wide screening for QTL. An association analysis between genotypes at the GH locus and traits was also carried out. The least squares analysis did not reveal the presence of genome-wide significant QTL affecting the traits, while the association study showed significant (P<0.01) associations between GH genotypes and fatness traits in M×P, but not in W×P. F2 pigs carrying the genotype C1A2/C4A2 at the GH locus displayed the thinnest backfat (21.76mm), while the ones carrying the genotype C2A2/C2A2 had the thickest (31.41mm).
Keywords:QTL  mapping  GH  association analysis  chromosome 12  pig
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