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Ubiquitously Expressed Proteins and Restricted Phenotypes: Exploring Cell-Specific Sensitivities to Impaired tRNA Charging
Institution:1. Neuromuscular Research Unit, Instituto de Investigación Sanitaria La Fe, Valencia, Spain;2. Unit of Genetics and Genomics of Neuromuscular and Neurodegenerative Disorders and Service of Genomics and Translational Genetics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain;3. Department of Clinical Neurophysiology, Hospital Universitari i Politècnic La Fe, Valencia, Spain;4. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Spain;5. Department of Neurology, Hospital Universitari i Politècnic La Fe, Valencia, Spain;6. Department of Medicine, University of Valencia, Valencia, Spain;1. School of Life Science and Biotechnology, KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea;2. Pohang Accelerator Laboratory, Pohang University of Science and Technology, 80 Jigokro-127-beongil, Nam-Gu, Pohang, Kyungbuk 37673, Republic of Korea;3. Medicinal Bioconvergence Research Center, Seoul National University, Suwon 16229, Republic of Korea;4. College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea
Abstract:
Keywords:aminoacyl-tRNA synthetases  tRNA charging  protein translation  peripheral neuropathy  developmental delay  recessive disease
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