Zum Problem der genetischen Rekombination von Bakteriophagen

Summary The mating theory ofVisconti andDelbrück describes quantitatively the recombination kinetics in phage. One special assumption of this theory is thepairwise mating of complete parental structures randomly chosen from the pool, which can lead to the production of a new recombinant particle. On the other hand it seems possible to assume a mechanism, by which the number of templates involved in the formation of a new replica is not restricted to two particles. The hypothesis of complete cooperation presented here suggests the participation ofN+1 random templates in the formation of a new replica carryingN recombination sites. Such a mechanism may be interpreted in different ways, e.g. by a partical replica model or by a partical pairing, which connects more than two parental structures. A differential equation is given, describing this assumption and leading to formulas very similar to those of the mating theory.

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