Computational RNomics: Structure identification and functional prediction of non-coding RNAs in silico |
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Authors: | LingLing Zheng LiangHu Qu |
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Affiliation: | ZHENG LingLing & QU LiangHu Key Laboratory of Gene Engineering of the Ministry of Education,State Key Laboratory for Biocontrol,Sun Yat-sen University,Guangzhou 510275,China |
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Abstract: | The eukaryotic genome contains varying numbers of non-coding RNA(ncRNA) genes.Computational RNomics takes a multidisciplinary approach,like information science,to resolve the structure and function of ncRNAs.Here,we review the main issues in Computational RNomics of data storage and management,ncRNA gene identification and characterization,ncRNA target identification and functional prediction,and we summarize the main methods and current content of computational RNomics. |
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Keywords: | non-coding RNA eukaryote computational RNomics |
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