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A new naturally acetylated triterpene saponin from Nigella sativa |
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| Authors: | Bhupendra Kumar Mehta Prabha Mehta |
| Institution: | a School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain 456 010, M.P., India b Govt. KRG (Autonomous) College, Gwalior, M.P., India c Institute of Pharmacy, Vikram University, Ujjain 456 010, M.P., India |
| Abstract: | A new glycosylated triterpene 1 was identified as 3-O-β-d-xylopyranosyl-(1→3)-α-l-rhamnopyranosyl-(1→4)-β-d-glucopyranosyl]-11-methoxy-16-hydroxy-17-acetoxy hederagenin from an ethanolic extract of seeds of Nigella sativa Linn. Identification of the naturally acetylated saponin was based on chemical and spectroscopic analyses including FABMS, 1H, 13C, and 2D NMR and DEPT. The saponin was a penta hydroxy pentacyclic triterpene, in which one hydroxyl group was acetylated and other one was methylated naturally. |
| Keywords: | Nigella sativa Seeds Ranunculaceae Ethanol extract Naturally acetylated saponin |
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