Inhibition of lipid synthesis in Bacillus amyloliquefaciens by inhibitors of protein synthesis

Inhibitors of protein synthesis reduce the level of lipid production in Bacillus amyloliquefaciens, both in growing cells and in non-dividing washed-cell suspensions. This effect is primarily on phospholipids rather than acetone-soluble lipids. Although the cells contain five major phospholipids the washed-cell supernatants contain only one phospholipid species whose accumulation is sensitive to chloramphenicol but insensitive to rifampicin.