Glycoproteins of Axonal Transport: Affinity Chromatography on Fucose-Specific Lectins |
| |
Authors: | S Gustavsson C Ohlson J O Karlsson |
| |
Institution: | Institute of Neurobiology, University of Goteborg, Goteborg, Sweden |
| |
Abstract: | Rapidly transported fucose-labeled glycoproteins from axons of rabbit retinal ganglion cells were solubilized with nonionic detergents. The solubilized components were subjected to affinity chromatography on three different fucose-specific lectins. A recently characterized fucose-specific lectin from Aleuria aurantia bound reversibly approximately 60% of the applied protein-bound radioactivity. The lectins from Lotus tetragonolobus and Ulex europaeus bound are very small proportions of the labeled rapidly transported glycoproteins. |
| |
Keywords: | Axonal transport Fucose-specific lectins |
|