| mRNA结构及其稳定性的关系 |
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| 引用本文： | 熊高飞,熊向阳,张吉翔.mRNA结构及其稳定性的关系[J].细胞生物学杂志,2006,28(4):513-517. |
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| 作者姓名： | 熊高飞 熊向阳 张吉翔 |
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| 作者单位： | 南昌大学第二附属医院消化科 分子医学重点实验室，南昌大学基础医学院生理学教研室，生物化学教研室，南昌大学第二附属医院消化科，分子医学重点实验室，南昌330006 南昌大学基础医学院生理学教研室，生物化学教研室，南昌330006，南昌330006，南昌330006 |
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| 基金项目： | 国家自然科学基金资助项目(No.30360037,No.30160032)~~ |
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| 摘 要： | mRNA结构与mRNA稳定性关系密切,mRNA稳定性与基因表达调控之间也有着紧密的联系。现从mRNA结构中所含的5'端帽结构、3'端poly(A)尾、5'非翻译区、3'非翻译区、编码区、富AU元件等方面综述了mRNA结构与mRNA稳定性之间的关系,为深入了解基因表达调控的分子机制提供理论基础。
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| 关 键 词： | mRNA结构 mRNA稳定性 基因表达 |
| 收稿时间： | 2005-11-03 |
| 修稿时间： | 2006-04-13 |
The Relationship between mRNA Structure and Its Stability |
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| Gao-Fei Xiong,Xiang-Yang Xiong,Ji-Xiang Zhang.The Relationship between mRNA Structure and Its Stability[J].Chinese Journal of Cell Biology,2006,28(4):513-517. |
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| Authors: | Gao-Fei Xiong Xiang-Yang Xiong Ji-Xiang Zhang |
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| Institution: | 1Department of Digestion, the Key Laboratory of Molecular Medicine, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China; 2Department of Physiology, Department of Biochemistry, Basical Medical College, Nanchang University, Nanchang 330006, China |
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| Abstract: | mRNA structure is closely correlated with mRNA stability which is involved in the regulation of gene expression. To better understand the molecular mechanisms of gene expression, the relationship between mRNA structure, including 5' cap structure, 3' poly(A) tail, 5' untranslated region et al., and mRNA stability was reviewed in this work. |
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| Keywords: | mRNA structure mRNA stability gene expression |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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