Antimicrobial activity of two novel coumarin derivatives: 3-cyanonaphtho[1,2-(e)] pyran-2-one and 3-cyanocoumarin |
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Authors: | Zaha A A Hazem A |
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Institution: | Amman University, Faculty of Pharmacy and Medical Sciences, Al-Sarw, Jordan. |
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Abstract: | The antimicrobial activity of the two novel coumarin derivatives, 3-cyanonaphthol1,2-(e)]pyran-2-one and 3-cyanocoumarin was determined. The two novel coumarin derivatives showed specific activity against most gram-positive organisms and yeast with lower activity against most gram-negative bacteria. The MIC values of compounds showed that they are largely active against E. coli to a lesser extent against S. aureus and C. albicans. |
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