实验动物致敏研究进展

实验动物致敏（laboratory Animal Allergy,LAA）,是一种职业过敏性疾病,造成人的呼吸道及皮肤发生炎症。该病在国外研究较多,过敏源是动物皮毛、尿液、唾液中的一类酸性小分子蛋白质;可以通过皮肤试验、放射过敏吸附试验及ELISA等方法检测易感人员。对易感人员可以通过控制环境中的过敏原来保护。目前国内尚无专门机构研究此病症,笔者综述了该职业性疾病的症状、机理、控制方法及国内外对该病症认识上的差异。

Research Progress of Laboratory Animal Allergy

Laboratory animal allergy（LAA） is a form of occupational hypersensitivity affecting the eyes,nose,skin and lower respiratory tract.The allergens are some lower molecular weight acid proteins involved in the animal hair,urine and spit.Questionnaire,skin prick testing,ELISA and lung function measurements can be employed in allergen survey.The sensitive workers may be protected by environment controlling.In this paper,the symptoms,mechanism and controlling of LAA are reviewed.