Molecular cloning and biochemical characterization of a novel cytochrome P450, flavone synthase II, that catalyzes direct conversion of flavanones to flavones |
| |
Authors: | Akashi T Fukuchi-Mizutani M Aoki T Ueyama Y Yonekura-Sakakibara K Tanaka Y Kusumi T Ayabe S |
| |
Affiliation: | Department of Applied Biological Science, Nihon University, Kanagawa, Japan. |
| |
Abstract: | Cytochrome P450 cDNAs, AFNS2 and TFNS5, were isolated from snapdragon and torenia petal cDNA libraries, respectively, based on the sequence homology with licorice CYP93B1 cDNA encoding (2S)-flavanone 2-hydroxylase. They were expressed in yeast and identified to encode flavone synthase II catalyzing direct conversion of flavanones to flavones probably via 2-hydroxyflavanones. |
| |
Keywords: | |
本文献已被 PubMed Oxford 等数据库收录! |
|