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Antimicrobial agents from higher plants: two dimethylbenzisochromans from Karwinskia humboldtiana |
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| Authors: | Lester A Mitscher Sitaraghav R Gollapudi David S Oburn Steven Drake |
| Institution: | Department of Medicinal Chemistry, University of Kansas Lawrence, KS 66045-2500, U.S.A. |
| Abstract: | Two new antimicrobial dimethylbenzisochromans were isolated from the roots of Karwinskia humboldtiana together with the known 7-acetyl-6,8-dimethoxy-3-methyl-l-naphthol. The structures and absolute configurations were determined by spectroscopic examination and by chemical transformation to the known quinones eleutherin and 7-methoxyeleutherin. |
| Keywords: | Rhamnaceae karwinaphthol A and B 2-acetyl-6 8-dimethoxy-3-methyl-l-naphthol eleutherin and 7-methoxyeleutherin antimicrobial activity |
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