Biosynthesis of nimbolide from [2-14C,(4R)4-3H1] mevalonic acid lactone in the leaves of Azadirachta indica期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Biosynthesis of nimbolide from [2-¹⁴C,(4R)4-³H₁] mevalonic acid lactone in the leaves of Azadirachta indica

Authors:	Donald E.U. Ekong Samuel A. Ibiyemi

Affiliation:	1. Chemistry Department, University of Ilorin, Ilorin, Nigeria

Abstract:	Nimbolide was biosynthesized from [2-¹⁴C, (4R)4-³H₁]mevalonic acid lactone in the leaves of Azadirachta indica. The nimbolide had a ³H:¹⁴C ratio of 3:5 which gives support to the suggestion of the involvement of a triterpenoid intermediate with a double bond at the Δ⁸⁽⁹)-position in the biosynthesis of nimbolide.

Keywords:	Meliaceae: nimbolide mevalonic acid lactone euphol butyrospermol tirucallol.
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