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Grindelane diterpenoids from grindelia squarrosa and G. Camporum |
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| Authors: | Barbara N Timmermann Joseph J Hoffmann Shivanand D Jolad Karl H Schram |
| Institution: | 1. University of Arizona, College of Pharmacy, Tucson, AZ 85721, U.S.A. |
| Abstract: | An acid fraction of the dichloromethane extract of Grindelia squarrosa and a neutral fraction of the ethyl acetate extract of Grindelia camporum yielded a number of previously known grindelane diterpenoids and flavonoids. Along with the known isolates, two new grindelane diterpenoids, 13-isogrindelic acid and 17-grindeloxy grindelic acid, from G. squarrosa were isolated and identified spectroscopically. |
| Keywords: | Asteraceae Astereae Soladiginae diterpene acids labdanes methyl 13-isogrindelate methyl 17-hydroxy grindelate methyl 17-grindeloxy grindelate grindelic acid derivatives flavonoids |
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