Oxepane diterpenoids sesquiterpene lactones from ‘zoapatle’ (montanoa tomentosa), a mexican plant with oxytocic activity

Investigation of the ‘tea’ prepared from the leaves of ‘zoapatle’ (Montanoa tomentosa), resulted in the isolation of the known biologically active oxepane diterpenoids zoapatanol and montanol, the known sesquiterpene lactones zoapatanolide A, C and D as well as two new biologically active oxepane diterpenoids and a new sesquiterpene lactone. The structures of the new compounds were established by spectroscopic methods.